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Updated: Jun 1, 2026
05:59
Green Synthesis of Quinoline-Based Ionic Liquid
Published on: September 27, 2024
2-Chloro-7-methyl-quinoline-3-carbaldehyde
Summary
The study analyzed the structure of a chloro-substituted quinoline compound. Its fused-ring system is planar, with the formyl group deviating slightly from this plane.
Area of Science:
- Crystallography and Molecular Structure
- Organic Chemistry
- Medicinal Chemistry
Background:
- Quinoline derivatives are prevalent in pharmaceuticals and materials science.
- Understanding the precise three-dimensional structure of novel quinoline compounds is crucial for structure-activity relationship studies.
Purpose of the Study:
- To elucidate the crystal structure and molecular geometry of the title compound, C(11)H(8)ClNO.
- To investigate the planarity of the quinoline fused-ring system and the orientation of the formyl substituent.
Main Methods:
- Single-crystal X-ray diffraction analysis was employed to determine the molecular structure.
- Analysis of bond lengths, bond angles, and torsion angles provided detailed geometric information.
Main Results:
- The quinoline fused-ring system of C(11)H(8)ClNO was found to be planar, with a root-mean-square deviation of 0.007 Å.
- The formyl group exhibited a slight deviation from the plane of the quinoline system, indicated by specific C-C-C-O torsion angles.
Conclusions:
- The planar nature of the quinoline core is a key structural feature of this compound.
- The observed conformation provides insights into the electronic and steric properties of the molecule, relevant for its potential applications.
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