2-Benzyl-myo-inositol monohydrate
Richard F G Fröhlich1, Graeme J Gainsford, Gavin F Painter
1Industrial Research Limited, PO Box 31-310, Lower Hutt, New Zealand.
Summary
The crystal structure of 2-benzyl-myo-inositol monohydrate was determined. This compound forms a 2D hydrogen-bonded network in its solid state.
Area of Science:
- Crystallography
- Molecular structure
- Supramolecular chemistry
Background:
- Myo-inositol derivatives are important in biological systems.
- Understanding the solid-state structure of such compounds is crucial for their applications.
Purpose of the Study:
- To determine the crystal structure of 2-benzyl-myo-inositol monohydrate.
- To investigate the hydrogen bonding interactions in the crystal.
Main Methods:
- Single-crystal X-ray diffraction was used to analyze the crystal structure.
- Structural analysis focused on hydrogen bonding patterns.
Main Results:
- The asymmetric unit contains one 2-benzyl-myo-inositol molecule and one water molecule.
- All hydroxyl (OH) protons participate in hydrogen bonding.
- The molecules form an infinite two-dimensional network through strong hydrogen bonds.
Conclusions:
- The crystal structure reveals a robust 2D hydrogen-bonded network mediated by hydroxyl groups and water.
- This supramolecular arrangement is a key feature of 2-benzyl-myo-inositol monohydrate in the solid state.
