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Updated: Jun 1, 2026

08:43
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
trans-4,5-Dihydr-oxy-1,3-bis-(4-methoxy-phen-yl)imidazolidine-2-thione
Abstract:
In the title compound, C(17)H(18)N(2)O(4)S, where one of the N-4-methoxy-phenyl fragments is disordered over two sets of sites, the five-membered ring exhibits a nearly half-chair conformation and the two hydroxyl groups lie on opposite sides of the five-membered ring. In the crystal, the mol-ecules are linked into sheets parallel to (100) via O-H⋯O and O-H⋯S hydrogen bonds.
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