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Updated: Jun 1, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
N,N'-Di-8-quinolyl-2,2'-(o-phenyl-ene-di-oxy)diacetamide
1Department of Biology and Chemistry, Changzhi University, Changzhi, Shanxi 046011, People's Republic of China.
Abstract:
In the title compound, C(28)H(22)N(4)O(4), the mol-ecule lies on a crystallographic twofold axis. The quinoline ring is essentially planar (give max or rms deviation 0.0186 Å), and the dihedral angle between the quinoline ring and the central benzene ring is 19.1 (4)°. Intra-molecular N-H⋯(N,O) and C-H⋯O hydrogen bonds contribute to the formation of the roughly planar configuration. The crystal packing is stabilized by inter-molecular C-H⋯O hydrogen bonds, and weak π-π inter-actions between the pyridine rings and central benzene rings of the neighboring mol-ecules [centroid-centroid separation = 3.9009 (6) Å].
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