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A dimeric sesquiterpene, gochnatiolide A.

Hui-Ping Xiong, Zhi-Jun Wu, Dong-Sheng Chen

Acta Crystallographica. Section E, Structure Reports Online

|May 18, 2011

Summary

This summary is machine-generated.

A novel dimeric sesquiterpene, derived from dehydro-zaluzanin C, was isolated from Ainsliaea henryi. This compound features a unique cyclohexane system linking two sesquiterpene lactone units.

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Area of Science:

Natural Products Chemistry
Organic Chemistry
Phytochemistry

Background:

Sesquiterpene lactones are a diverse class of natural products with a wide range of biological activities.
Ainsliaea species are known sources of various bioactive compounds.
Dehydro-zaluzanin C is a known sesquiterpene lactone.

Purpose of the Study:

To isolate and characterize a novel dimeric sesquiterpene from Ainsliaea henryi.
To elucidate the chemical structure of the isolated compound.

Main Methods:

Isolation of the title compound from Ainsliaea henryi using chromatographic techniques.
Structure elucidation using spectroscopic methods (e.g., NMR, Mass Spectrometry).

Main Results:

A novel dimeric sesquiterpene, 5'a-hydroxy-1',3,6,8'-tetrakis(methylene)-3a,4,5,5',5'a,6,6',6a,7,7',7'a,8',9a,9b,10'a,10'b-hexadecahydrospiro[azuleno[4,5-b]furan-9(2H),3'-[3H]benz[1,8]azuleno[4,5-b]furan]-2,2',8,9'(1'H,3H,4'H)-tetrone acetone 0.92-solvate, was isolated.
The compound is a dimeric sesquiterpene formed by a cyclohexane system connecting two dehydro-zaluzanin C units.

Conclusions:

The study successfully isolated and characterized a new dimeric sesquiterpene from Ainsliaea henryi.
The findings contribute to the understanding of sesquiterpene diversity and biosynthesis in the Ainsliaea genus.