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Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

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Published on: February 5, 2018

6-Bromo-pyridine-2-carboxamide.

Feng Xue¹, Shen-Gui Ju

¹College of Chemistry and Chemical Engineering, Nanjing University of Technology, Xinmofan Road No. 5 Nanjing, Nanjing 210009, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online

|May 18, 2011

Summary

This summary is machine-generated.

This study details the crystal structure of a brominated organic compound. It reveals intra-molecular hydrogen bonds forming a ring and inter-molecular bonds creating sheet-like structures in the solid state.

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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

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Area of Science:

Crystal chemistry
Organic chemistry
Supramolecular chemistry

Background:

Understanding the hydrogen bonding patterns in organic molecules is crucial for predicting their solid-state properties.
The specific compound C(6)H(5)BrN(2)O presents an interesting case for crystallographic analysis due to its functional groups.

Purpose of the Study:

To elucidate the crystal structure of the title compound C(6)H(5)BrN(2)O.
To identify and characterize the hydrogen bonding interactions present in the crystal lattice.

Main Methods:

Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
Analysis of the crystal structure focused on identifying hydrogen bond donors and acceptors.

Main Results:

An intra-molecular N-H⋯N hydrogen bond was observed, forming a stable S(5) ring motif.
Inter-molecular bifurcated N-H⋯(O,O) hydrogen bonds were identified, linking molecules into extended sheets.
The sheets propagate along the (100) direction in the crystal.

Conclusions:

The crystal packing of C(6)H(5)BrN(2)O is dominated by a combination of intra- and inter-molecular hydrogen bonding.
The observed hydrogen bonding network dictates the formation of sheet-like supramolecular architecture.