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Related Concept Videos

Indicators02:39

Indicators

Certain organic substances change color in dilute solution when the hydronium ion concentration reaches a particular value. For example, phenolphthalein is a colorless substance in any aqueous solution with a hydronium ion concentration greater than 5.0 × 10−9 M (pH < 8.3). In more basic solutions where the hydronium ion concentration is less than 5.0 × 10−9 M (pH > 8.3), it is red or pink. Substances such as phenolphthalein, which can be used to determine the pH of a solution, are called...
ortho&ndash;para-Directing Activators: &ndash;CH3, &ndash;OH, &ndash;&NoBreak;NH2, &ndash;OCH301:11

ortho–para-Directing Activators: –CH3, –OH, –⁠NH2, –OCH3

All ortho–para directors, excluding halogens, are activating groups. These groups donate electrons to the ring, making the ring carbons electron-rich. Consequently, the reactivity of the aromatic ring towards electrophilic substitution increases. For instance, the nitration of anisole is about 10,000 times faster than the nitration of benzene. The electron-donating effect of the methoxy group in anisole activates the ortho and para positions on the ring and stabilizes the corresponding...

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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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3-(4-Hydroxy-phenyl-imino)indolin-2-one.

Yan Meng1

  • 1School of Environmental Engineering, Chang'an University, South Second Cycle Road 368, Xi'an 710054, Shannxi, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online
|May 18, 2011
PubMed
Summary
This summary is machine-generated.

This study details the crystal structure of a novel organic compound, C(14)H(10)N(2)O(2). The research reveals specific molecular arrangements and hydrogen bonding patterns that form a three-dimensional network.

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Area of Science:

  • Crystallography
  • Organic Chemistry
  • Supramolecular Chemistry

Background:

  • Understanding the three-dimensional arrangement of molecules is crucial in chemistry.
  • Hydrogen bonding plays a significant role in molecular self-assembly and crystal engineering.

Purpose of the Study:

  • To elucidate the crystal structure of the title compound, C(14)H(10)N(2)O(2).
  • To analyze the intermolecular interactions, specifically hydrogen bonding, within the crystal lattice.

Main Methods:

  • Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
  • Analysis of hydrogen bonding networks using graph-set notation.

Main Results:

  • The dihedral angle between the indole and benzene rings was determined to be 61.63(4)°.
  • Centrosymmetric dimers were formed via N-H⋯O hydrogen bonds, described by the R(2)(2)(8) motif.
  • A three-dimensional network was established through additional O-H⋯O and C-H⋯O hydrogen bonds.

Conclusions:

  • The crystal structure of C(14)H(10)N(2)O(2) exhibits a specific dihedral angle between its aromatic rings.
  • Intermolecular hydrogen bonding dictates the formation of dimers and a supramolecular 3D network.