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Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
1-(2-Methyl-6-nitro-4-phenyl-3-quinol-yl)ethanone
Abstract:
In the title compound, C(18)H(14)N(2)O(3), the quinoline ring system is almost planar [maximum deviation = 0.013 (2) Å] and forms a dihedral angle of 60.36 (7)° with the benzene ring. The nitro group is slightly twisted from the attached quinoline ring system, forming a dihedral angle of 9.06 (19)°. In the crystal packing, inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into chains propagating in [010].
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