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Updated: Jun 1, 2026

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
4-Methoxy-benzene-carbothio-amide
Abstract:
The asymmetric unit of the title compound, C(8)H(9)NOS, contains two independent mol-ecules with the meth-oxy groups oriented in opposite conformations. The mean planes of the carbothio-amide groups are tilted by 7.88 (15) and 11.16 (9)° from the mean planes of the benzene rings. In the crystal, the mol-ecules form dimers via intermolecular N-H⋯S inter-molecular hydrogen bonds, resulting in eight-membered rings of R(2) (2)(8) graph-set motif. The dimers are further linked by C-H⋯O hydrogen bonds into chains along the c axis. Adjacent chains inter-act through inter-molecular N-H⋯S hydrogen bonds, generating eight-membered rings of R(4) (2)(8) graph-set motif.
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