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Updated: Jun 1, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
2-Hydr-oxy-N'-(2-hydr-oxy-4-methoxy-benzyl-idene)-3-methyl-benzohydrazide monohydrate
You-Yue Han1, Yong-Hong Li, Qiu-Rong Zhao
1Department of Chemistry and Life Science, Chuzhou University, Chuzhou, Anhui 239000, People's Republic of China.
Abstract:
In the title compound, C(16)H(16)N(2)O(4)·H(2)O, the dihedral angle between the two benzene rings is 12.4 (2)° and the mol-ecule adopts an E configuration with respect to the C=N bond. There are intra-molecular O-H⋯N and O-H⋯O hydrogen bonds in the hydrazone mol-ecule, which both generate S(6) rings. In the crystal structure, mol-ecules are linked by N-H⋯O and O-H⋯O hydrogen bonds, forming layers parallel to the ab plane. The crystal studied was a non-merohedral twin with a domain ratio of 0.887 (3):0.113 (3).
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