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Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
2,3,5-Trimethyl-1,4-hydro-quinone
Jun Dai1, Min-Hao Xie, Ya-Ling Liu
1Jiangsu Institute of Nuclear Medicine, Wuxi 214063, People's Republic of China.
Abstract:
The mol-ecule of the title compound, C(9)H(12)O(2), is approximately planar (mean atomic deviation = 0.0346 Å) and disposed about a crystallographic centre of symmetry. The H atom of the benzene ring is disordered over four orientations, with occupancies of 0.100 (3) and 0.401 (3) at the C atoms in the 2- and 3-positions and the same at their symmetric location. The H atoms of methyl group at the 2-position are disordered over two positions of equal occupancy. In the crystal structure, adjacent mol-ecules are linked through O-H⋯O hydrogen bonds, forming a two-dimensional network.
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