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Updated: Jun 1, 2026

Green Synthesis of Quinoline-Based Ionic Liquid
Published on: September 27, 2024
(+)-hexacyclinol
David M Pinkerton1, Martin G Banwell, Anthony C Willis
1Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 0200, Australia.
Abstract:
A SAMPLE OF THE TITLE COMPOUND [SYSTEMATIC NAME: (1aS,2aS,3S,5aS,6aS,7R,7aS,7bS,8R,8aS,10R)-7-hydr-oxy-3-(1-meth-oxy-1-methyl-ethyl)-10-(2-methyl-1-propen-yl)-1a,5a,6a,7,7a,7b,8,8a-octa-hydro-2H-8,2a-(epoxy-methano)phenanthro[2,3-b:6,7-b']bis-oxirene-2,5(3H)-dione], C(23)H(28)O(7), was generated by enanti-oselective synthesis. There are three mol-ecules of the compound in the crystallographic asymmetric unit. Hydrogen bonding between alcohol H atoms and keto groups of adjacent mol-ecules appears to stabilize the structure. The compound is enanti-omerically pure but the absolute configuration could not be determined directly in this study. Accordingly, the illustrated configuration was assigned on the basis of the nature of the chiral nonracemic precursor used in the synthesis.
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