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Updated: Jun 1, 2026
11:01
Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
2-(2-Pyridylsulfan-yl)acetic acid
Xiao-Feng Li1, Yan An, Hui-Guo Chen
1Institute of Marine Materials Science and Engineering, Shanghai Maritime University, Shanghai 201306, People's Republic of China .
Summary
This study details the crystal structure of a compound containing sulfur, nitrogen, and oxygen. Molecules arrange into zigzag chains through specific intermolecular interactions, revealing insights into crystal packing dynamics.
Area of Science:
- Crystallography
- Solid-state chemistry
- Molecular structure analysis
Background:
- Understanding the three-dimensional arrangement of atoms in crystalline solids is fundamental in chemistry.
- Intermolecular forces play a crucial role in determining crystal packing and material properties.
- The specific compound C(7)H(7)NO(2)S was selected for structural investigation.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(7)H(7)NO(2)S.
- To identify and characterize the intermolecular interactions governing crystal packing.
- To describe the resulting supramolecular architecture.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of atomic positions and bond lengths/angles.
- Identification of non-covalent interactions such as hydrogen bonds and van der Waals forces.
Main Results:
- All non-hydrogen atoms of C(7)H(7)NO(2)S were found to lie on a crystallographic mirror plane.
- The crystal structure is characterized by intermolecular C-H⋯O and O-H⋯N contacts.
- These interactions result in the formation of infinite zigzag chains aligned parallel to the [010] crystallographic direction.
Conclusions:
- The crystal structure of C(7)H(7)NO(2)S exhibits a high degree of symmetry due to the presence of a mirror plane.
- Specific intermolecular interactions dictate the self-assembly of molecules into one-dimensional chains.
- The findings contribute to the understanding of structure-property relationships in organic crystalline materials.
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