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Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
8H-Chromeno[2',3':4,5]imidazo[2,1-a]isoquinoline
Abstract:
The title compound, C(18)H(12)N(2)O, comprises two aromatic fragments, viz., imidazo[2,1-a]isoquinoline and benzene, linked by oxygen and methyl-ene bridges. Despite the absence of a common conjugative system within the mol-ecule, it adopts an essentially planar conformation with an r.m.s. deviation of 0. 036 Å. In the crystal, due to this structure, mol-ecules form stacks along the b axis by π⋯π stacking inter-actions, with shortest C⋯C distances in the range 3.340 (4)-3.510 (4) Å. The mol-ecules are bound by inter-molecular C-H⋯O inter-actions within the stacks and C-H⋯π inter-actions between the stacks.
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