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Updated: Jun 1, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
2-[(E)-(3,4-Dimethyl-isoxazol-5-yl)imino-meth-yl]phenol
Abstract:
The title compound, C(12)H(12)N(2)O(2), has been synthesized by the reaction of 5-amino-3,4-dimethyl-isoxazole and salicyladehyde. The mol-ecule adopts an E configuration about the central C=N double bond. The dihedral angle between the isoxazole and phenyl rings is 4.2 (2)° and an intra-molecular O-H⋯N hydrogen bond generates an S(6) ring motif. The crystal studied was a non-merohedral twin with a domain ratio of 0.834 (4):0.166 (4).
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