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Updated: Jun 1, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
Ethyl 2-[3-(4-nitro-benzo-yl)thio-ureido]benzoate
Abstract:
In the title compound, C(17)H(15)N(3)O(5)S, the nitro and thio-ureido groups are twisted by 7.2 (7) and 21.4 (2)°, respectively, from the nitro-benzene ring plane whereas the thio-ureido and the ethyl ester group make dihedral angles of 43.0 (1) and 18.0 (2)°, respectively, with the benzene rings to which they are attached. Intra-molecular N-H⋯O hydrogen-bonding inter-actions are observed. In the crystal, inter-molecular N-H⋯O hydrogen bonds connect the mol-ecules into chains running along the a axis.
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