Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

IUPAC Nomenclature of Aldehydes01:16

IUPAC Nomenclature of Aldehydes

Aldehydes are named based on the systematic nomenclature rules set by the IUPAC. For acyclic aldehydes, the longest carbon chain containing the aldehydic (–CHO) group is considered the parent chain. The aldehyde is named by replacing the last letter “e” in the hydrocarbon name with “al”. For instance, a simple, seven-carbon-membered acyclic aldehyde is called heptanal, derived from heptane. The carbon chain is numbered starting from the aldehydic carbon, although the aldehydic carbon’s locant...
Organic Compounds03:02

Organic Compounds

All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
Nomenclature of Carboxylic Acid Derivatives: Acid Halides, Esters, and Acid Anhydrides01:16

Nomenclature of Carboxylic Acid Derivatives: Acid Halides, Esters, and Acid Anhydrides

Naming Acid Halides
The IUPAC and common names of acid halides are derived from the corresponding carboxylic acids, by changing “ic acid” to “yl halide.” For example, as shown below, the IUPAC name ethanoyl chloride is derived from ethanoic acid, and the common name, acetyl chloride, is obtained from acetic acid.
IUPAC Nomenclature of Carboxylic Acids01:16

IUPAC Nomenclature of Carboxylic Acids

IUPAC names of carboxylic acids are systematically derived following a few rules discussed below.
For acyclic saturated monocarboxylic acids, the longest hydrocarbon chain containing the –COOH carbon is identified as the parent chain. Then, the last -e of the parent hydrocarbon name is replaced with a suffix -oic acid.
Alkylation of β-Diester Enolates: Malonic Ester Synthesis01:14

Alkylation of β-Diester Enolates: Malonic Ester Synthesis

Malonic ester synthesis is a method to obtain α substituted carboxylic acids from ꞵ-diesters such as diethyl malonate and alkyl halides.
Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives01:35

Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives

Just like β-keto acids—which upon thermal decarboxylation form ketones—β-dicarboxylic acids undergo decarboxylation to generate monocarboxylic acids with the liberation of carbon dioxide.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Machine Learning-Assisted Discovery of Thermally Activated Delayed Fluorescence Emitters.

Journal of fluorescence·2026
Same author

Outcomes of Left Bundle Branch Area Pacing in Heart Failure Patients: A Systematic Review.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·2026
Same author

Outcomes of Non-operatively Managed Achilles Tendon Rupture: A Retrospective, Single-Centre Study.

Cureus·2026
Same author

A review on integrated isotopic and receptor model approaches for urban REE source appointment.

Environmental geochemistry and health·2026
Same author

Clinical features, prognosis, and treatment outcomes of diphtheria in children: a retrospective cohort study at children's hospital, Sukkur.

BMC infectious diseases·2026
Same author

Clinical outcomes of regenerative endodontic procedures compared with apexification in young immature necrotic teeth: a systematic review of randomized controlled trials.

Odontology·2026

Related Experiment Video

Updated: Jun 1, 2026

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
14:18

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

3-(4-Ethoxy-benzo-yl)propionic acid.

Sajid Ali, Aurangzeb Hasan, Nasim Hasan Rama

    Acta Crystallographica. Section E, Structure Reports Online
    |May 18, 2011
    PubMed
    Summary
    This summary is machine-generated.

    This study details the crystal structure of a key intermediate compound, C(12)H(14)O(4), crucial for synthesizing biologically active heterocyclic compounds. Molecular interactions like hydrogen bonds and C-H⋯π contacts were identified, offering insights into its chemical behavior.

    More Related Videos

    Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
    06:52

    Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

    Published on: October 30, 2018

    Related Experiment Videos

    Last Updated: Jun 1, 2026

    A Strategy for Sensitive, Large Scale Quantitative Metabolomics
    14:18

    A Strategy for Sensitive, Large Scale Quantitative Metabolomics

    Published on: May 27, 2014

    Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
    06:52

    Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

    Published on: October 30, 2018

    Area of Science:

    • Organic Chemistry
    • Crystallography
    • Medicinal Chemistry

    Background:

    • The title compound, C(12)H(14)O(4), serves as a vital building block in organic synthesis.
    • Heterocyclic compounds are prevalent in pharmaceuticals and biologically active molecules.

    Purpose of the Study:

    • To elucidate the crystal structure of the title compound.
    • To understand the intermolecular interactions governing the compound's solid-state arrangement.
    • To provide foundational data for its application in synthesizing complex heterocyclic structures.

    Main Methods:

    • Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
    • Analysis of intermolecular interactions, including hydrogen bonding and C-H⋯π contacts.

    Main Results:

    • The crystal structure of C(12)H(14)O(4) was successfully determined.
    • Intermolecular O-H⋯O and C-H⋯O hydrogen bonds were identified as key linking forces.
    • C-H⋯π interactions between the benzene ring and methylene groups were observed, contributing to the crystal packing.

    Conclusions:

    • The determined crystal structure provides a detailed understanding of the title compound's solid-state organization.
    • The identified hydrogen bonds and C-H⋯π contacts are critical for the compound's stability and reactivity.
    • This structural information is valuable for the rational design and synthesis of novel biologically active heterocyclic compounds.