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Updated: Jun 1, 2026
06:46
Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
1-(3,4-Dihydroxy-phen-yl)-2-(4-fluoro-phen-yl)ethanone.
1School of Chemical and Material Engineering, Jiangnan University, Lihu Road No. 1800 Wuxi, Wuxi 214122, People's Republic of China.
Summary
The crystal structure of C(14)H(11)FO(3) reveals a significant dihedral angle between aromatic rings. Intramolecular and intermolecular hydrogen bonds influence the compound's molecular arrangement and packing in the solid state.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding the three-dimensional structure of organic molecules is crucial for predicting their properties and reactivity.
- Hydrogen bonding plays a significant role in molecular recognition and the formation of crystal lattices.
- The study of diaryl compounds provides insights into conformational preferences and electronic interactions.
Purpose of the Study:
- To determine and analyze the crystal structure of the title compound, C(14)H(11)FO(3).
- To investigate the conformational aspects, specifically the dihedral angle between the aromatic rings.
- To identify and characterize intra- and intermolecular hydrogen bonding interactions.
Main Methods:
- Single-crystal X-ray diffraction was employed to obtain the crystal structure data.
- The crystal structure was solved and refined using standard crystallographic software.
- Analysis of the crystal structure included the determination of bond lengths, bond angles, and intermolecular interactions.
Main Results:
- The crystal structure of C(14)H(11)FO(3) was successfully determined.
- A notable dihedral angle of 69.11(8)° was observed between the two aromatic rings.
- An intramolecular O-H⋯O hydrogen bond was identified, along with intermolecular O-H⋯O interactions contributing to crystal packing.
Conclusions:
- The crystal structure analysis provides a detailed understanding of the molecular geometry of C(14)H(11)FO(3).
- The observed dihedral angle suggests a specific conformational preference in the solid state.
- Hydrogen bonding interactions are key determinants of the observed crystal packing, influencing the overall supramolecular architecture.
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