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Updated: Jun 1, 2026
08:43
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
3-Methoxy-4-(4-nitro-benz-yloxy)-benzaldehyde.
1College of Sciences, Tianjin University of Science and Technology, Tianjin 300457, People's Republic of China.
Summary
This study analyzes the crystal structure of a novel compound, C(15)H(13)NO(5). The vanillin and nitro-benzene groups exhibit a specific dihedral angle, with crystal packing stabilized by intermolecular interactions.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Understanding molecular interactions is crucial for designing new materials.
- The vanillin and nitro-benzene moieties are common in organic synthesis and drug discovery.
Purpose of the Study:
- To elucidate the crystal structure of the compound C(15)H(13)NO(5).
- To investigate the spatial arrangement and intermolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and intermolecular contacts.
Main Results:
- The vanillin group forms a dihedral angle of 4.95(8)° with the nitro-benzene ring.
- Crystal packing is stabilized by intermolecular C-H⋯O interactions, forming chains along the c axis.
Conclusions:
- The determined crystal structure provides insights into the solid-state behavior of this compound.
- The intermolecular interactions suggest potential for self-assembly and supramolecular chemistry applications.
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