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Updated: Jun 1, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
4,4'-Dichloro-2,2'-(piperazine-1,4-diyldimethyl-ene)diphenol
Koji Kubono1, Yuki Tsuno, Keita Tani
1Division of Natural Sciences, Osaka Kyoiku University, Kashiwara, Osaka 582-8582, Japan.
Abstract:
In the titile compound, C(18)H(20)Cl(2)N(2)O(2), the piperazine ring adopts a chair conformation. The mol-ecule has a non-crystallographic inversion centre in the middle of the piperazine ring at approximate position (3/4, 1/8, 3/8). There are intra-molecular O-H⋯N hydrogen bonds forming S(6) ring motifs. Inter-molecular C-H⋯O hydrogen bonds generate anti-parallel C(5) chain motifs propagating along the b axis, forming sheets parallel to the bc plane with a first-level graph-set S(6)C(5)R(6) (6)(26).
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