N'-(4-Bromo-benzyl-idene)isonicotino-hydrazide

Area of Science:

• Organic Chemistry
• Crystallography

Background:

• Hydrazide derivatives are important in medicinal chemistry.
• Schiff bases derived from aldehydes and hydrazides exhibit diverse biological activities.

Purpose of the Study:

• To synthesize and characterize a new compound with potential applications.
• To investigate the structural and bonding properties of the synthesized molecule.

Main Methods:

• Synthesis of the title compound C(13)H(10)BrN(3)O via reaction of isonicotinohydrazide and 4-bromo-benzaldehyde.
• Single crystal X-ray diffraction analysis to determine molecular structure and crystal packing.

Main Results:

• The synthesized compound C(13)H(10)BrN(3)O was successfully prepared.
• The dihedral angle between the benzene and pyridine rings was determined to be 8.60(12)°.
• Intermolecular hydrogen bonding interactions (C-H⋯O and N-H⋯O) were identified as key stabilizing forces in the crystal lattice.

Conclusions:

• The study successfully synthesized and characterized a novel organic compound.
• The structural analysis provides insights into the molecular geometry and intermolecular forces governing crystal formation.
• The findings contribute to the understanding of structure-property relationships in related chemical entities.