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6-Bromo-2-naphthol-piperazine (2/1)
1State Key Laboratory of Crystalline Materials, Shandong University, Jinan 250100, People's Republic of China and School of Chemistry & Chemical Engineering, Shandong University, Jinan 250100, People's Republic of China.
Summary
This study details the crystal structure of a compound formed by 6-bromo-2-naphthol and piperazine. Hydrogen bonds link these molecules, forming chains with specific interactions.
Area of Science:
- Crystallography
- Supramolecular Chemistry
- Organic Chemistry
Background:
- Understanding molecular interactions is key in crystal engineering.
- Piperazine and naphthol derivatives are common in chemical synthesis.
Purpose of the Study:
- To elucidate the crystal structure of the 2:1 compound formed between 6-bromo-2-naphthol and piperazine.
- To analyze the hydrogen bonding and intermolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was used to determine the molecular and crystal structure.
- Analysis of hydrogen bonding (O-H⋯N, N-H⋯O) and C-H⋯π interactions was performed.
Main Results:
- The piperazine molecule adopts a chair conformation.
- Two molecules of 6-bromo-2-naphthol are linked to one piperazine molecule via O-H⋯N hydrogen bonds.
- Weak N-H⋯O hydrogen bonds and C-H⋯π interactions contribute to the formation of chains propagating along the [100] direction.
Conclusions:
- The crystal structure reveals a specific arrangement driven by hydrogen bonding and π-π stacking.
- This detailed structural analysis provides insights into the supramolecular assembly of organic compounds.
