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Updated: Jun 1, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
5,5'-Dimeth-oxy-2,2'-[2,2-dimethyl-propane-1,3-diylbis(nitrilo-methyl-idyne)]diphenol
Abstract:
The asymmetric unit of the title Schiff base compound, C(21)H(26)N(2)O(4), consists of four crystallographically independent mol-ecules, viz. A, B, C and D. The A and D, and the B and C mol-ecules are related by a pseudo-inversion centre, and the remaining pairs of mol-ecules differ in the orientations of one of the meth-oxy groups. In each independent mol-ecule, intra-molecular O-H⋯N hydrogen bonds generate two S(6) ring motifs. The dihedral angles between the benzene rings in mol-ecules A, B, C and D are 65.86 (19), 50.41 (19), 68.59 (19) and 50.85 (19)°, respectively. In the crystal structure, mol-ecules are linked by C-H⋯O hydrogen bonds, forming R(2) (2)(8) dimers. In addition, weak C-H⋯π inter-actions are observed.
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