(E)-N'-(4-Chloro-benzyl-idene)-3,4,5-trimethoxy-benzohydrazide
Yu-Min Wang1, Zhen-Dong Zhao, Yu-Xiang Chen
1Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing 210042, People's Republic of China.
Summary
Researchers synthesized a novel compound, C(17)H(17)ClN(2)O(4), using specific precursors. Crystal structure analysis revealed stabilization through various hydrogen bonding interactions, offering insights into molecular assembly.
Area of Science:
- Organic Chemistry
- Crystallography
- Supramolecular Chemistry
Background:
- Understanding the synthesis and structural properties of novel organic compounds is crucial in medicinal chemistry and materials science.
- Benzohydrazide derivatives and substituted benzaldehydes are common building blocks for complex organic molecules.
Purpose of the Study:
- To synthesize a new chemical entity, C(17)H(17)ClN(2)O(4).
- To elucidate the crystal structure and identify the intermolecular forces governing its packing.
Main Methods:
- Chemical synthesis involving the reaction of 3,4,5-trimethoxy-benzohydrazide with 4-chloro-benzaldehyde.
- Single-crystal X-ray diffraction to determine the molecular and crystal structure.
Main Results:
- Successful synthesis of the target compound with the molecular formula C(17)H(17)ClN(2)O(4).
- Crystal structure analysis revealed the compound's arrangement in the solid state.
- Identification of stabilizing interactions including intramolecular C-H⋯O and intermolecular N-H⋯O and C-H⋯O hydrogen bonds.
Conclusions:
- The synthesized compound C(17)H(17)ClN(2)O(4) possesses a defined crystal structure.
- Hydrogen bonding plays a significant role in the crystal packing and stability of this molecule.
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