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Updated: Jun 1, 2026
07:06
Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
2-Hydr-oxy-N'-[(E)-(3-hydr-oxy-2-naphth-yl)methyl-ene]benzohydrazide
Summary
Hydrogen bonds dictate the molecular shape and crystal structure of a novel organic compound. Intermolecular bonds form chains, influencing the overall solid-state arrangement.
Area of Science:
- Crystallography
- Organic Chemistry
- Molecular Structure
Background:
- Understanding intermolecular forces is crucial for predicting material properties.
- Hydrogen bonding plays a significant role in molecular conformation and crystal packing.
- The specific compound C(18)H(14)N(2)O(3) was investigated for its structural characteristics.
Purpose of the Study:
- To elucidate the molecular conformation of C(18)H(14)N(2)O(3) influenced by hydrogen bonding.
- To determine the crystal structure and intermolecular interactions.
- To analyze the role of hydrogen bonds in the solid-state arrangement.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond distances and angles to identify hydrogen bonding interactions.
- Dihedral angle measurements to quantify the molecular conformation.
Main Results:
- Intramolecular O-H⋯N and N-H⋯O hydrogen bonds were identified, influencing molecular conformation.
- The benzene and naphthalene planes exhibit a dihedral angle of 11.54(5)°.
- Intermolecular O-H⋯O hydrogen bonds link molecules into chains along the [01] direction.
Conclusions:
- Hydrogen bonding is a key factor governing the molecular conformation and crystal packing of C(18)H(14)N(2)O(3).
- The observed chain-like structure formed by intermolecular hydrogen bonds is a significant feature of the crystal lattice.
- This study provides insights into structure-property relationships driven by hydrogen bonding in organic crystals.
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