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Updated: Jun 1, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
(E)-Methyl 3-(2-methyl-1-phenyl-sulfonyl-1H-indol-3-yl)but-2-enoate
Abstract:
In the title compound, C(20)H(19)NO(4)S, the indole ring system is planar [r.m.s. deviation = 0.023 (2) Å]. The sulfonyl-bound phenyl ring is almost perpendicular to the indole ring system [dihedral angle = 86.75 (7)°]. The ester group is almost planar (r.m.s. deviation = 0.030 Å) and is oriented at an angle of 62.53 (5)° with respect to the indole ring system. Mol-ecules are linked into a two-dimensional network parallel to the ab plane by inter-molecular C-H⋯O hydrogen bonds.
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