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Updated: Jun 1, 2026
08:43
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
(E)-4-Bromo-N-(2,4-dimethoxy-benzyl-idene)aniline
Summary
This study details the crystal structure of a Schiff base compound, C(15)H(14)BrNO(2). The molecule exhibits specific E configuration and intermolecular interactions, forming rows in its crystal lattice.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Schiff base compounds are versatile organic molecules with diverse applications.
- Understanding the solid-state structure of Schiff bases is crucial for predicting their properties and designing new materials.
Purpose of the Study:
- To elucidate the detailed crystal structure of the Schiff base compound C(15)H(14)BrNO(2).
- To analyze the molecular geometry, including bond configurations and substituent orientations.
- To investigate intermolecular interactions and their role in crystal packing.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the three-dimensional structure.
- Analysis of bond lengths, bond angles, dihedral angles, and deviations from planarity.
- Identification and characterization of intermolecular interactions, such as hydrogen bonds and van der Waals forces.
Main Results:
- The compound C(15)H(14)BrNO(2) was confirmed to possess an E configuration around the C=N bond.
- Methoxy substituents showed minimal deviation from the dimethoxy-phenyl ring plane.
- The crystal structure revealed the formation of inversion-related dimers linked by weak C-H⋯N and C-H⋯O interactions, forming rows parallel to the b axis.
Conclusions:
- The study provides a comprehensive structural characterization of the Schiff base compound.
- The identified crystal packing and intermolecular interactions offer insights into the solid-state behavior of this class of compounds.
- This structural data can serve as a foundation for further research into the functional properties and potential applications of related Schiff bases.
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