(E)-6-Chloro-N'-(3,5-dichloro-2-hydroxy-benzyl-idene)-nicotinohydrazide
1College of Chemistry and Pharmacy, Qingdao Agricultural University, Shandong 266109, People's Republic of China.
A novel Schiff base compound was synthesized and characterized. Its crystal structure reveals a nearly planar molecule with intramolecular hydrogen bonding and intermolecular interactions forming infinite chains.
Area of Science:
- Organic Chemistry
- Crystallography
- Supramolecular Chemistry
Background:
- Schiff bases are versatile organic compounds with diverse applications.
- Understanding the crystal packing and intermolecular interactions is crucial for material design.
Purpose of the Study:
- To synthesize a new Schiff base compound with the chemical formula C(13)H(8)Cl(3)N(3)O(2).
- To elucidate the molecular and crystal structure of the synthesized compound.
Main Methods:
- Condensation reaction between 3,5-dichloro-salicyl-aldehyde and 6-chloro-nicotinic acid hydrazide.
- Single crystal X-ray diffraction analysis to determine the molecular and crystal structure.
Main Results:
- The Schiff base compound was successfully synthesized in 95% ethanol.
- The molecule exhibits a nearly planar conformation with a dihedral angle of 1.9(2)° between aromatic ring planes.
- An intramolecular O-H⋯N hydrogen bond and intermolecular N-H⋯O hydrogen bonds forming infinite chains along the [100] direction were observed.
Conclusions:
- The synthesized Schiff base possesses a well-defined molecular structure.
- The observed hydrogen bonding network dictates the crystal packing and supramolecular architecture.
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