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Updated: Jun 1, 2026
09:45
Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
N-(1,3-Thia-zol-2-yl)benzamide
Summary
This study details the molecular structure of a novel organic compound. The research reveals a nonplanar configuration and the formation of hydrogen-bonded dimers in its crystalline state.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding the three-dimensional structure of organic molecules is crucial for predicting their properties and reactivity.
- The formation of intermolecular interactions, such as hydrogen bonds, significantly influences crystal packing and material characteristics.
Purpose of the Study:
- To elucidate the crystal structure and intermolecular interactions of the title compound, C(10)H(8)N(2)OS.
- To investigate the role of hydrogen bonding in the self-assembly of this molecule in the solid state.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of the crystal structure focused on bond lengths, bond angles, and intermolecular interactions.
Main Results:
- The title compound, C(10)H(8)N(2)OS, exhibits a nonplanar molecular geometry.
- A significant dihedral angle of 43.6(1)° was observed between the two aromatic rings.
- Two molecules associate via N-H⋯N hydrogen bonds around a center of inversion, forming a hydrogen-bonded dimer.
Conclusions:
- The crystal structure of C(10)H(8)N(2)OS is characterized by a nonplanar conformation.
- Intermolecular N-H⋯N hydrogen bonding drives the formation of dimeric units in the crystal lattice.
- This structural insight contributes to the understanding of molecular recognition and self-assembly in organic solids.
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