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Updated: Jun 1, 2026
09:45
Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
1,5-Bis[(E)-cyclo-pentyl-idene]thio-carbono-hydrazide
Summary
This study reveals intramolecular hydrogen bonds and disordered cyclopentyl rings in a C(11)H(18)N(4)S molecule. Intermolecular hydrogen bonds form dimers in the crystal structure.
Area of Science:
- Crystallography
- Supramolecular Chemistry
- Organic Chemistry
Background:
- Understanding molecular interactions is crucial in crystal engineering.
- Hydrogen bonding plays a significant role in molecular self-assembly.
- Conformational flexibility can influence crystal packing.
Purpose of the Study:
- To elucidate the crystal structure of the title molecule C(11)H(18)N(4)S.
- To investigate the types and strengths of hydrogen bonding interactions.
- To analyze the conformational behavior of the cyclopentyl rings.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bond distances and angles.
- Assessment of conformational disorder in the cyclopentyl rings.
Main Results:
- An intramolecular N-H⋯N hydrogen bond was identified with a distance of 2.558(3) Å.
- The two cyclopentyl rings exhibit conformational disorder in 1:1 and 2:1 ratios.
- Weak intermolecular N-H⋯S hydrogen bonds link molecules into centrosymmetric dimers.
Conclusions:
- The crystal structure is stabilized by both intramolecular and intermolecular hydrogen bonds.
- Conformational disorder of the cyclopentyl rings is a key feature of this crystal lattice.
- The observed hydrogen bonding patterns provide insights into the supramolecular assembly of this compound.
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