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Related Experiment Video

Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives

Facile Preparation of 4-Substituted Quinazoline Derivatives

Published on: February 15, 2016

8-Bromo-2-methyl-quinoline.

Lin-Tao Yang¹, Fang Shen, Jiao Ye

¹College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online

|May 18, 2011

Summary

This summary is machine-generated.

The crystal structure of C(10)H(8)BrN reveals a near-planar quinoline system with molecules arranged face-to-face. This packing arrangement, characterized by specific centroid-centroid distances, lacks hydrogen bonding in the solid state.

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Green Synthesis of Quinoline-Based Ionic Liquid

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Published on: September 27, 2024

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Last Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives

Facile Preparation of 4-Substituted Quinazoline Derivatives

Published on: February 15, 2016

Green Synthesis of Quinoline-Based Ionic Liquid

Green Synthesis of Quinoline-Based Ionic Liquid

Published on: September 27, 2024

Area of Science:

Crystallography
Organic Chemistry
Materials Science

Background:

Understanding the solid-state structure of organic compounds is crucial for predicting their physical and chemical properties.
Quinoline derivatives are important scaffolds in medicinal chemistry and materials science.

Purpose of the Study:

To elucidate the crystal structure of the title compound, C(10)H(8)BrN.
To analyze the molecular arrangement and intermolecular interactions within the crystal lattice.

Main Methods:

Single-crystal X-ray diffraction was employed to determine the three-dimensional structure.
Analysis of bond lengths, bond angles, and intermolecular distances was performed.

Main Results:

The crystal structure of C(10)H(8)BrN was successfully determined.
A small dihedral angle of 0.49(16)° between the quinoline rings indicates a nearly planar conformation.
Molecules are arranged in a face-to-face manner with a centroid-centroid distance of 3.76 Å between adjacent molecules.
No significant intermolecular hydrogen bonding was observed.

Conclusions:

The crystal packing of C(10)H(8)BrN is dominated by π-π stacking interactions between quinoline systems.
The observed structural features provide insights into the intermolecular forces governing the solid state of this compound.