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Updated: Jun 1, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
N'-(Di-2-pyridylmethyl-ene)benzo-hydrazide
This study details the molecular structure of a Schiff base (C(18)H(14)N(4)O), highlighting an N-H⋯N hydrogen bond and intermolecular C-H⋯N hydrogen-bonding. These findings contribute to understanding Schiff base crystal structures.
Area of Science:
- Crystal Engineering
- Supramolecular Chemistry
- Organic Chemistry
Background:
- Schiff bases are versatile organic compounds with diverse applications.
- Understanding intermolecular interactions is crucial for designing functional materials.
- Hydrogen bonding plays a significant role in molecular assembly and crystal packing.
Purpose of the Study:
- To elucidate the crystal structure of the title Schiff base (C(18)H(14)N(4)O).
- To investigate the specific hydrogen bonding interactions within the crystal lattice.
- To characterize the molecular packing arrangement.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond distances and angles provided insights into the chemical bonding.
- Intermolecular interactions, including hydrogen bonding, were identified and analyzed.
Main Results:
- The crystal structure of Schiff base C(18)H(14)N(4)O was successfully determined.
- An intramolecular N-H⋯N hydrogen bond was observed with a distance of 2.624(2) Å.
- An intermolecular C-H⋯N hydrogen-bonding ring motif (R(2)(2)(6)) was identified in the molecular packing.
Conclusions:
- The study provides a detailed structural characterization of the Schiff base.
- The identified hydrogen bonding patterns influence the overall molecular assembly and crystal structure.
- This work contributes to the fundamental understanding of Schiff base supramolecular chemistry.
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