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Updated: Jun 1, 2026

11:45
Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
1-(2-Chloro-acet-yl)-3-methyl-2,6-bis-(3,4,5-trimethoxy-phen-yl)piperidine-4-one
Abstract:
In the crystal structure of the title compound, C(26)H(32)ClNO(8), the piperidine ring is in a twist-chair conformation, with puckering parameters Q = 0.655 (4) Å, θ = 93.1 (1) and ϕ = 254.4 (3)°. The ortho C atoms of the piperidine ring deviate from the plane defined by the remaining ring atoms by 0.380 (3) and -0.250 (3) Å.
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