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Updated: Jun 1, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
1,3-Dihydr-oxy-2-(hydroxy-meth-yl)propan-2-aminium 2,2-dichloro-acetate
Abstract:
The title compound, C(4)H(12)NO(3) (+)·C(2)HCl(2)O(2) (-), was obtained from dichloro-acetic acid and 2-amino-2-(hydroxy-meth-yl)propane-1,3-diol. In the crystal structure, the cations and anions are connected by inter-molecular N-H⋯O and O-H⋯O hydrogen bonding, forming a two-dimensional array parallel to (001). The crystal used for analysis was a merohedral twin, as indicated by the Flack parameter of 0.67 (6).
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