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Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins

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Oxonium 2-carb-oxy-3-(2-fur-yl)acrylate.

Wen-Xian Liang¹, Gang Wang, Zhi-Rong Qu

¹Ordered Matter Science Research Center, College of Chemistry and Chemical Engineering, Southeast University, Nanjing 210096, People's Republic of China.

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|May 18, 2011

Summary

This summary is machine-generated.

This study reveals the crystal structure of H(3)O(+)·C(8)H(5)O(5) (-), highlighting a 1D chain framework formed by hydrogen bonds. The structure is further stabilized by π-π interactions, crucial for understanding molecular assembly.

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Area of Science:

Crystallography
Materials Science
Supramolecular Chemistry

Background:

Understanding the self-assembly of molecular compounds is key in materials science.
Hydrogen bonds and π-π interactions are fundamental forces driving crystal structure formation.
The specific compound H(3)O(+)·C(8)H(5)O(5) (-) presents an interesting case for structural analysis.

Purpose of the Study:

To elucidate the crystal structure of the title compound, H(3)O(+)·C(8)H(5)O(5) (-).
To identify and characterize the intermolecular interactions responsible for the observed crystal packing.
To provide insights into the factors governing the stability of this molecular framework.

Main Methods:

Single-crystal X-ray diffraction was employed to determine the atomic arrangement.
Analysis of hydrogen bonding networks (O-H⋯O) was performed.
Investigation of π-π stacking interactions, including centroid-centroid distances, was conducted.

Main Results:

The crystal structure exhibits a one-dimensional chain framework along the [001] direction.
Neighboring cations (H(3)O(+)) and anions (C(8)H(5)O(5) (-)) are linked by robust O-H⋯O hydrogen bonds.
π-π interactions with a centroid-centroid distance of 3.734(3) Å further stabilize the crystal lattice.

Conclusions:

The crystal structure of H(3)O(+)·C(8)H(5)O(5) (-) is characterized by a 1D chain assembly driven by hydrogen bonding.
π-π interactions play a significant role in the overall structural stability.
This detailed structural understanding contributes to the broader knowledge of supramolecular chemistry and crystal engineering.