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Updated: Jun 1, 2026
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Facile Protocol for the Synthesis of Self-assembling Polyamine-based Peptide Amphiphiles (PPAs) and Related Biomaterials
Published on: June 25, 2018
2-(Methoxy-carbon-yl)anilinium dihydrogen phosphate.
Summary
This study characterizes a methyl-anthranilate derivative, revealing its crystal structure. The compound forms dimers through hydrogen bonds, creating a stacked network in the crystal lattice.
Area of Science:
- Crystallography
- Chemical Crystallography
- Organic Chemistry
Background:
- Methyl-anthranilate is a naturally occurring compound with various applications.
- Derivatives of methyl-anthranilate can exhibit unique chemical and physical properties.
- Understanding the crystal structure of such derivatives is crucial for predicting their behavior.
Purpose of the Study:
- To determine the crystal structure of a specific methyl-anthranilate derivative, C(8)H(10)NO(2) (+)·H(2)PO(4) (-).
- To analyze the intermolecular interactions and packing arrangement within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to elucidate the crystal structure.
- The asymmetric unit was analyzed to identify the cation and anion components.
- Hydrogen bonding and other intermolecular contacts were identified and characterized.
Main Results:
- The crystal structure consists of 2-(methoxy-carbonyl)anilinium cations and dihydrogen phosphate anions.
- A dihedral angle of 22.94(9)° was observed between the benzene ring and the methyl ester group in the cation.
- Adjacent cations and anions form dimers via N-H⋯O and O-H⋯O hydrogen bonds.
- A network of stacked cation and anion dimers was observed along the b axis due to additional N-H⋯O and C-H⋯O contacts.
Conclusions:
- The study provides a detailed structural characterization of the title compound.
- The identified hydrogen bonding network and packing arrangement offer insights into the solid-state properties of this methyl-anthranilate derivative.
- This structural information can be valuable for further research on related compounds and their applications.
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