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Updated: Jun 1, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
4-[(Z)-(2-Eth-oxy-4-oxochroman-3-yl-idene)methyl-amino]benzene-sulfonamide monohydrate
Abstract:
In the mol-ecule of the title compound, C(18)H(18)N(2)O(5)S·H(2)O, the heterocyclic ring adopts a twisted conformation, while the aromatic rings are oriented at a dihedral angle of 45.46 (3)°. Intra-molecular C-H⋯O and N-H⋯O inter-actions result in the formations of planar five- and six-membered rings. In the crystal structure, N-H⋯O hydrogen bonds link the NH(2) and SO(2) groups through R(2) (2)(8) ring motifs, while C-H⋯O and N-H⋯O hydrogen bonds result in the formation of R(2) (1)(7) ring motifs. N-H⋯O and O-H⋯O hydrogen bonds link the uncoordinated water mol-ecules, forming a polymeric network. A weak C-H⋯π inter-action is also present.
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