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Updated: Jun 1, 2026
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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
3-[(5-Methyl-furan-2-yl)methyl-ene]-1,5-dioxaspiro-[5.5]undecane-2,4-dione
Wu-Lan Zeng1, Hua-Xiang Zhang, Fang-Fang Jian
1Microscale Science Institute, Department of Chemistry and Chemical Engineering, Weifang University, Weifang 261061, People's Republic of China.
Abstract:
There are two crystallographically independent mol-ecules in the asymmetric unit of the title compound, C(15)H(16)O(5). In each, the 1,3-dioxane ring is in an envelope conformation with the C atom common to the cyclo-hexane ring forming the flap. The dihedral angles between the five essentially planar [maximum deviations from the least-squares planes of 0.049 (3) and 0.042 (3) Å] atoms of the 1,3-dioxane ring and the furan ring in the two mol-ecules are 7.15 (1) and 6.80 (1)°. The crystal structure is stabilized by weak inter-molecular C-H⋯O hydrogen bonds.
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