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Updated: Jun 1, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
(E)-N'-(3,4-Dihydroxy-benzyl-idene)-4-nitro-benzohydrazide.
Feng Qiu1, Xiao-Jing He, Ya-Xin Sun
1Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
This study details the crystal structure of a Schiff base compound, C(14)H(11)N(3)O(5). Researchers identified specific molecular configurations, hydrogen bonding, and layered crystal packing, revealing insights into its solid-state properties.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Schiff base compounds are versatile organic molecules with diverse applications.
- Understanding the solid-state structure is crucial for predicting material properties.
Purpose of the Study:
- To elucidate the crystal structure and intermolecular interactions of a novel Schiff base compound.
- To characterize the hydrogen bonding network and molecular conformation.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and dihedral angles provided structural insights.
- Hydrogen bond analysis identified specific intermolecular and intramolecular interactions.
Main Results:
- The Schiff base compound C(14)H(11)N(3)O(5) exhibits a dihedral angle of 1.6(1)° between its benzene rings.
- An intramolecular O-H⋯O hydrogen bond and an E configuration about the C=N bond were observed.
- Molecules self-assemble into layers parallel to the (101) plane via O-H⋯O, N-H⋯O, and C-H⋯O hydrogen bonds.
- A hydroxyl group displays positional disorder with occupancies of 0.643(5) and 0.357(5).
Conclusions:
- The crystal structure reveals specific conformational preferences and intermolecular forces governing self-assembly.
- The observed hydrogen bonding network and disorder provide a foundation for further studies on related Schiff bases.
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