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Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
(1R,2R)-N,N'-Diisobutyl-N,N'-dimethyl-cyclo-hexane-1,2-diamine
Prisca K Eckert1, Viktoria H Gessner, Carsten Strohmann
1Anorganische Chemie, Technische Universität Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany.
Abstract:
The title compound, C(16)H(34)N(2), is a chiral diamine with fixed R configuration at both stereogenic carbon centres of the cyclo-hexane backbone. Due to their different substituents, the two N atoms also become stereogenic. In the crystal structure, the configuration at one of the two nitro-gen centres is fixed, with the free electron pair pointing inward and the isobutyl group in a trans position towards the cyclo-hexane backbone resulting in an R configuration. The isobutyl group at the second N atom, however, is disordered with 75% S configuration and 25% R configuration. In both cases, the isobutyl group is arranged in a trans position towards the cyclo-hexane backbone.
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