N'-(5-Chloro-2-hydroxy-benzyl-idene)-4-hydroxy-benzohydrazide
1Department of Chemistry, Shangqiu Normal University, Shangqiu 476000, People's Republic of China.
Summary
This study details the synthesis of a novel Schiff base compound. Its crystal structure reveals a trans configuration stabilized by intramolecular hydrogen bonds and a 3D network formed by intermolecular interactions.
Area of Science:
- Organic Chemistry
- Crystallography
- Supramolecular Chemistry
Background:
- Schiff bases are versatile organic compounds with diverse applications.
- Understanding molecular conformation and intermolecular interactions is crucial for material design.
Purpose of the Study:
- To synthesize and characterize a new Schiff base compound.
- To elucidate the crystal structure and hydrogen bonding patterns.
Main Methods:
- Chemical synthesis involving 5-chloro-salicylaldehyde and 4-hydroxy-benzohydrazide.
- Single-crystal X-ray diffraction analysis to determine molecular and crystal structure.
Main Results:
- The Schiff base compound C(14)H(11)ClN(2)O(3) was successfully synthesized.
- The molecule adopts a trans configuration with a dihedral angle of 40.1° between benzene rings.
- Intramolecular O-H⋯N and intermolecular N-H⋯O/O-H⋯O hydrogen bonds form a 3D crystal network.
Conclusions:
- The synthesized Schiff base exhibits a defined molecular conformation stabilized by intramolecular hydrogen bonding.
- Intermolecular hydrogen bonds dictate the formation of a robust three-dimensional supramolecular architecture in the solid state.
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