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Right hemispheric function in normals, affective disorder and schizophrenia.

M Borde¹, A Roy, E J Davis

¹Milin Borde, MD., DPM., DNB., Consultant Psychiatrist, Davis Institute of Neuropsychiatry, Kanke, Ranchi - 834006.

Indian Journal of Psychiatry

|May 18, 2011

Summary

The happy-sad chimeric faces test reveals right hemispheric function differences. Healthy individuals and depressives show a left hemifacial bias, unlike manic and schizophrenic patients, suggesting right hemisphere dysfunction in the latter groups.

Keywords:

LHF bias affective disorder hemispheric function schizophrenia

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Area of Science:

Neuroscience
Cognitive Psychology
Clinical Psychology

Background:

The happy-sad chimeric faces test is a validated tool for assessing right hemispheric function.
This test typically induces a left hemifacial bias (LHF bias) in right-handed individuals.

Purpose of the Study:

To investigate right hemispheric function in patients with mania, depression, and schizophrenia using the happy-sad chimeric faces test.
To determine if LHF bias differs between healthy controls and patient groups.

Main Methods:

41 healthy controls and 19 patients (manic, depressive, schizophrenic) were tested.
All participants were strictly right-handed.
The happy-sad chimeric faces test was administered to assess LHF bias.

Main Results:

Healthy controls and patients with depression exhibited a significant LHF bias.
Patients with mania and schizophrenia did not display a significant LHF bias.
A notable difference in LHF bias was observed between the healthy/depressive groups and the manic/schizophrenic groups.

Conclusions:

The findings suggest intact right hemispheric function in healthy individuals and those with depression, as indicated by significant LHF bias.
The absence of significant LHF bias in manic and schizophrenic patients points towards potential right hemispheric dysfunction in these conditions.
The happy-sad chimeric faces test may serve as a valuable indicator for identifying right hemispheric dysfunction in psychiatric disorders.