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Demographic, breast-feeding, and nutritional trends among children with type 1 diabetes mellitus

Manash P Baruah1, Ariachery C Ammini, Madan L Khurana

  • 1Department of Endocrinology, Excel center, Ulubari, Guwahati, Assam-781 007, India.

Indian Journal of Endocrinology and Metabolism
|May 18, 2011
PubMed

Insights

This study found no significant differences in demographic or environmental factors, including breastfeeding, between children with recent-onset type 1 diabetes mellitus and controls. Further research with larger sample sizes is recommended.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Immunology

Background:

  • Type 1 diabetes mellitus (T1DM) pathogenesis involves genetic susceptibility and environmental triggers.
  • Progressive loss of pancreatic beta cells is a hallmark of T1DM.
  • Understanding T1DM etiology is crucial for prevention and treatment strategies.

Purpose of the Study:

  • To compare the impact of demographic and environmental factors on children with recent-onset T1DM.
  • To investigate the role of breastfeeding in T1DM development.
  • To identify potential risk factors in children under 18 years old.

Main Methods:

  • A hospital-based case-control study was conducted.
  • 43 consecutive patients with recent-onset T1DM (≤1 year) were included.
  • Matched controls without diabetes or dysglycemia were used for comparison.

Main Results:

  • A peak incidence of T1DM was observed in early adolescence, with seasonal variation in winter months.
  • No significant differences were found between patients and controls regarding birth order, delivery mode, parental factors, diet, breastfeeding, or family migration.
  • Growth characteristics and nutritional status were similar between groups.

Conclusions:

  • Demographic and common environmental factors studied did not show significant differences between T1DM cases and controls.
  • Breastfeeding does not appear to be a differentiating factor in this cohort.
  • Larger population studies are needed to further investigate T1DM etiology.
Abstract

Keywords:
Type 1 diabetes mellitus demographybreast-feedingdiabetestype 1 diabetes mellitus etiology

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