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Changes in plasma iron levels following Carboplatin administration

I Nielsen1, S Sartori, D Tassinari

  • 1ARCISPEDALE ST ANNA,DIV MED 2,CORSO GIOVECCA 203,I-44100 FERRARA,ITALY. ARCISPEDALE ST ANNA,SERV ONCOL MED,I-44100 FERRARA,ITALY. OSPED CIVILE,DIV PNEUMOL,TRESIGALLO,ITALY.

International Journal of Oncology
|May 18, 2011
PubMed
Summary

Carboplatin chemotherapy increases plasma iron and impairs red blood cell production (erythropoiesis). These changes do not predict transfusion needs, suggesting platinum compounds affect iron metabolism through multiple mechanisms.

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