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04:56
Assessment of Social Transmission of Food Preferences Behaviors
Published on: January 25, 2018
Eating disturbance in behavioural-variant frontotemporal dementia
1Neuroscience Research Australia, Barker St, Randwick, Sydney, NSW, 2031, Australia. o.piguet@neura.edu.au
Journal of Molecular Neuroscience : MN
|May 18, 2011
Summary
Behavioural-variant frontotemporal dementia (bvFTD) causes significant eating changes. Research links these disturbances to brain network and hypothalamus dysregulation, offering potential therapeutic targets.
Area of Science:
- Neuroscience
- Neurology
- Neurodegeneration
Background:
- Behavioural-variant frontotemporal dementia (bvFTD) is a progressive neurodegenerative disorder.
- bvFTD is characterized by cognitive, personality, and behavioral changes.
- Eating disturbances, including overeating and sweet food preference, are common in bvFTD.
Purpose of the Study:
- To review the literature on eating abnormalities in bvFTD.
- To examine the clinical characteristics and biological correlates of these eating disturbances.
- To explore the role of the hypothalamus in eating regulation in bvFTD.
Main Methods:
- Literature review of current research on eating abnormalities in bvFTD.
- Analysis of clinical characteristics and biological correlates.
- Examination of the contribution of the hypothalamus to eating regulation.
Main Results:
- Eating disturbances in bvFTD are linked to dysregulation in the orbitofrontal-insular-striatal brain network.
- Degeneration and dysregulation within the hypothalamus are associated with significant feeding disturbances in bvFTD.
- These findings highlight the neural basis of eating abnormalities in this condition.
Conclusions:
- The orbitofrontal-insular-striatal network and hypothalamus are key areas involved in eating dysregulation in bvFTD.
- Understanding these biological correlates can inform the development of therapeutic strategies.
- Further research into hypothalamic function may yield new treatments for bvFTD-related feeding issues.
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