Related Experiment Video
Updated: Jun 1, 2026

Standardized In vitro Assays to Visualize and Quantify Interactions between Human Neutrophils and Staphylococcus aureus Biofilms
Published on: June 8, 2022
Does Staphylococcus aureus nasal colonization involve biofilm formation?
Bernhard Krismer1, Andreas Peschel
1Interfaculty Institute of Microbiology & Infection Medicine, Cellular & Molecular Microbiology Section, University of Tübingen, Germany.
Abstract:
The human anterior nares are used by Staphylococcus aureus as the major colonization site in 20-30% of the human population. Eradication of S. aureus carriage can significantly reduce the numbers of nosocomial infections. However, the interactions governing the colonization process have remained elusive and it has been debated whether S. aureus adopts a biofilm-like state in the nose. We summarize recent studies on staphylococcal living conditions during nasal colonization, which favour a dispersed rather than a biofilm-related mode of growth during S. aureus nasal colonization. This notion is of major importance for future directions in the development of new decolonization strategies.
More Related Videos
Related Concept Videos
Biofilms
Staphylococcal Skin Infections
Microbiota of the Respiratory Tract
Colonisation of Pathogens
Development of the Oral Microbiota
Clinical Significance of Antibiotic Resistance

