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Transgenic Organisms

Transgenic Organisms

Transgenic Organisms

Transgenic Organisms

Transgenic Plants

Transgenic Plants

Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...

What is Genetic Engineering?

What is Genetic Engineering?

Plant Breeding and Biotechnology

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.

Recombinant DNA

Recombinant DNA

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Related Experiment Video

Updated: Jun 1, 2026

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

[Advances on transgene containment technologies].

Qian Zhang¹, Jin-Feng Zhang, Wen-Feng Fu

¹National Engineering Laboratory for Tree Breeding, Key Laboratory for Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, the Tree and Ornamental Plant Breeding and Biotechnology Laboratory of State Forestry Administration, Beijing Forestry University, Beijing 100083, China. zhangqian9722@163.com

Yi Chuan = Hereditas

|May 19, 2011

Summary

This summary is machine-generated.

Ensuring the safety of genetically modified organisms (GMOs) is crucial for their application. This review highlights transgene containment technologies, with GM-gene-deletor technology showing promise for secure GMO use.

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An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

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Transgene Expression in Cultured Cells Using Unpurified Recombinant Adeno-Associated Viral Vectors

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Published on: October 20, 2023

Area of Science:

Biotechnology
Genetics
Molecular Biology

Context:

The application of transgenic organisms is significantly limited by biosecurity concerns.
Technological advancements are actively addressing the biosecurity challenges of genetically modified organisms.
Transgene containment is a key area of focus in current transgenic research.

Purpose:

To review and evaluate various transgene containment technologies for ensuring the biosecurity of transgenic organisms.
To identify promising strategies for the safe application of genetically modified organisms.
To suggest future directions for developing novel transgene containment technologies.

Summary:

This paper reviews several transgene containment technologies, including marker-free, safety marker, chloroplast, terminator, male sterility, and 'GM-gene-deletor' technologies.
The 'GM-gene-deletor' technology is highlighted as a particularly promising approach for enhancing the biosecurity of transgenic organisms.
The study also proposes strategies for the development of new containment technologies.

Impact:

Provides a comprehensive overview of current transgene containment strategies.
Identifies 'GM-gene-deletor' technology as a significant advancement for safe transgenic organism application.
Offers insights into future research and development in GMO biosecurity.