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Updated: Jun 1, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Intraparotid facial nerve neurofibroma in neurofibromatosis type 1
Deniz Tuna Edizer1, Yusuf Hajizade, Emin Karaman
1Otorhinolaryngology Department, Bayrampasa State Hospital, Istanbul, Turkey. deniztunaedizer@yahoo.com
Abstract:
Benign tumors of the nerve sheath are of 2 types: schwannoma and neurofibroma. Neurofibromas are most commonly found with neurofibromatosis type 1 and characterized by incorporation of the nerve fibers within their matrix. Both benign and malignant tumors can affect the facial nerve. These tumors can be intrinsic or extrinsic; in other words, it can originate from the facial nerve itself or from a contiguous structure or a metastatic disease. Actually, extrinsic tumors are far more common than intrinsic tumors. Intraparotid location of benign tumors of the facial nerve sheath is considered a rare event compared with intratemporal location.
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