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Pleomorphic adenomas recurrences within the parapharyngeal space
Şenol Polat1, Gediz Murat Serin, Ozmen Öztürk
1Department of Otorhinolaryngology, Acıbadem University Medical Faculty, Acıbadem Healthcare Group, Neurology and Oncology Hospital, Istanbul, Turkey. senolpolat@yahoo.com
The Journal of Craniofacial Surgery
|May 19, 2011
Summary
Recurrent pleomorphic adenomas (PAs) in the parapharyngeal space often require multiple surgeries. Radiation therapy (RT) is recommended for multinodular disease, tumor spillage, or residual tumor after surgery.
Area of Science:
- Otolaryngology
- Head and Neck Surgery
- Oncology
Background:
- Recurrent pleomorphic adenomas (PAs) in the parapharyngeal space present significant management challenges.
- Multinodular recurrence and residual disease are common after initial surgical interventions.
Purpose of the Study:
- To evaluate the outcomes of treating recurrent pleomorphic adenomas (PAs) in the parapharyngeal space.
- To identify key factors influencing the management of these challenging tumors.
Main Methods:
- Retrospective review of 9 patients with recurrent parapharyngeal space PAs.
- Analysis of surgical history, imaging, clinical examinations, and treatment outcomes, including revision surgeries and radiation therapy (RT).
Main Results:
- Four patients experienced multinodular recurrence after the first revision surgery.
- A total of 12 reoperations were performed across the patient cohort.
- Four patients had persistent recurrence or residual disease post-treatment.
Conclusions:
- Revision surgery combined with radiation therapy (RT) is recommended for multinodular disease, tumor spillage, or residual PAs.
- Histopathology, surgical technique, proximity to vital structures, and adjuvant radiotherapy are critical for managing recurrent PAs.
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