Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating Variability in Extracellular Vesicle Characterization Across Measurement Techniques.

Journal of extracellular biology·2026
Same author

Reply: Remote Incisions as an Alternative to Mastectomy Scars for Breast Tissue Expander-to-Implant Exchange: A Propensity Score-Matched Analysis.

Plastic and reconstructive surgery·2026
Same author

Notch signaling regulates the secretion of pro-metastatic factors in extracellular vesicles in liposarcoma.

Cancer letters·2026
Same author

Spatially Anchored Regulatory State Inference in Melanoma.

bioRxiv : the preprint server for biology·2026
Same author

Integrative spatial multi-omics reveal niche-specific inflammatory signaling and differentiation hierarchies in AML.

iScience·2026
Same author

Validation of a Seven-Gene Predictive SIGNature for the Efficacy of Immuno-Oncology PD-1 Inhibitors in Patients with Sarcoma.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
Same journal

The Rise of Nerve Transfers: Tracing a National Evolution Toward the Postgrafting Era in Brachial Plexus Injury Management.

Annals of plastic surgery·2026
Same journal

Response to: The Cost of Matching into Plastic Surgery.

Annals of plastic surgery·2026
Same journal

Comprehensive Review of Pressure Sores: Pathophysiology, Prevention, and Surgical Management.

Annals of plastic surgery·2026
Same journal

Evaluating the Efficacy and Safety of Venous Flow-Through Flaps in Hand Reconstructive Surgery: A Systematic Review.

Annals of plastic surgery·2026
Same journal

Experimental Rat Peripheral Nerve Models: Surgical Exposures and Applications.

Annals of plastic surgery·2026
Same journal

The Cost of Matching into Plastic Surgery.

Annals of plastic surgery·2026
See all related articles

Related Experiment Video

Updated: Jun 1, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

Published on: July 28, 2020

Desmoid tumor: current multidisciplinary approaches.

Richard N Berri1, Donald P Baumann, John E Madewell

  • 1Departments of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. rnberri@mdanderson.org

Annals of Plastic Surgery
|May 19, 2011
PubMed
Summary
This summary is machine-generated.

Desmoid tumors, or aggressive fibromatosis, are rare, locally invasive tumors without metastatic potential. Multidisciplinary expert teams are crucial for optimal management, balancing treatment efficacy with minimized morbidity.

More Related Videos

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
13:41

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

Related Experiment Videos

Last Updated: Jun 1, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

Published on: July 28, 2020

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
13:41

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Desmoid tumors, also known as aggressive fibromatosis, are rare neoplasms.
  • Characterized by local infiltration and high recurrence rates, they lack metastatic potential.
  • Commonly found in the abdomen, abdominal wall, or proximal extremities.

Purpose of the Study:

  • To review the management of desmoid tumors.
  • To emphasize the importance of a multidisciplinary approach in optimizing patient outcomes.
  • To highlight strategies for maximizing therapeutic efficacy while minimizing treatment-related morbidities.

Main Methods:

  • Literature review on desmoid tumor characteristics and management.
  • Discussion of the role of multidisciplinary teams in surgical and oncological care.
  • Analysis of treatment strategies balancing efficacy and morbidity.

Main Results:

  • Desmoid tumors present significant challenges due to their infiltrative and recurrent nature.
  • Surgical resection requires careful consideration to maintain function and cosmesis.
  • Multidisciplinary collaboration is key to achieving superior functional and aesthetic results.

Conclusions:

  • Effective management of desmoid tumors necessitates a coordinated multidisciplinary approach.
  • Integrating expertise from surgical oncologists, plastic surgeons, medical oncologists, and radiation oncologists is vital.
  • This collaborative strategy aims to enhance therapeutic outcomes and reduce treatment-related complications.